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Inversion of Exons 1-7 of MSH Gene Is An Infrequent Cause In One Population Of Lynch Syndrome

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Dr. Richard Boland, at Baylor University, Dallas, Texas, has identified a reason some mutations may not appear within traditional testing in those who had a positive family history but tested negative with germline testing and not indicating a clear mutation. The explanation may be inversion of exons 1-7 of the MSH2 gene.

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